R N A   B I O L O G Y

  2022
 

Localized translation of cell junction mRNAs is required for epithelial cell polarity

Chin A, Bergeman J, Communal L, Boulais J, Mes-Masson A-M, Lécuyer E

Under review.

  2021
 

Persistent mRNA localization defects and cell death in ALS neurons caused by transient cellular stress.

Markmiller S, Sathe S, Server KL, Nguyen TB, Fulzele A, Cody N, Javaherian A, Broski S, Finkbeiner S, Bennett EJ, Lécuyer E, Yeo GW

Cell Reports. 2021, 36: 109685. doi: 10.1016/j.celrep.2021.109685.

(https://pubmed.ncbi.nlm.nih.gov/34496257/)

 

Puromycin labeling coupled with proximity ligation assays to define sites of mRNA translation in Drosophila embryos and human cells.

Chin A, Lécuyer E

Methods Mol Biol. 2021, 2381: 267-284.

(https://pubmed.ncbi.nlm.nih.gov/34590282/)

 

RNA interference (RNAi) screening in cultured Drosophila cells.

Padilla JA, Chin A, Patel D, Jolivet P, Lécuyer E

Methods Mol Biol. 2021, 2381: 267-284.

(https://pubmed.ncbi.nlm.nih.gov/34590272/)

  2020
 

Translating messages in different neighbouhoods.

Chin A, Lécuyer E

Dev Cell. 2020, 54: 691-693.

(https://pubmed.ncbi.nlm.nih.gov/32991835/)

 

A large-scale binding and functional map of human RNA-binding proteins.

Van Nostrand EL*, Freese P*, Pratt GA*, Wang X*, Wei X*, Xiao R*, Blue SM, Chen JY, Cody NAL, Dominguez D, Olson S, Sundararaman B, Zhan L, Bazile C, Bouvrette LPB, Bergalet J, Duff MO, Garcia KE, Gelboin-Burkhart C, Hochman M, Lambert NJ, Li H, McGurk MP, Nguyen TB, Palden T, Rabano I, Sathe S, Stanton R, Su A, Wang R, Yee BA, Zhou B, Louie AL, Aigner S, Fu XD¶, Lécuyer E¶, Burge CB¶, Graveley BR¶, Yeo GW¶

*=Co-first authors; ¶=Co-corresponding authors.

Nature. 2020, 583: 711-719.

(https://pubmed.ncbi.nlm.nih.gov/32728246/)

 

Expanded encyclopaedias of DNA elements in the human and mouse genomes.

ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z

Nature. 2020, 583: 699-710.

(https://pubmed.ncbi.nlm.nih.gov/32728249/)

 

Perspectives on ENCODE. 

ENCODE Project Consortium, Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM

Nature. 2020, 583: 693-698.

(https://pubmed.ncbi.nlm.nih.gov/32728248/)

 

Staufen1 localizes to the mitotic spindle and controls the localization of RNA populations to the spindle. 

Hassine S, Bonnet-Magnaval F, Benoit Bouvrette LP, Doran B, Ghram M, Bouthillette M, Lécuyer E, DesGroseillers L

J Cell Sci. 2020, 133: jcs247155. doi: 10.1242/jcs.247155.

(https://pubmed.ncbi.nlm.nih.gov/32576666/)

 

Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila. 

Bergalet J, Patel D, Legendre F, Lapointe C, Benoit Bouvrette LP, Chin A, Blanchette M, Kwon E, Lécuyer E

Cell Rep. 2020, 30:3339-3352.

(https://pubmed.ncbi.nlm.nih.gov/32160541/)

 

oRNAment: a database of putative RNA binding protein target sites in the transcriptomes of model species. 

Benoit Bouvrette LP, Bovaird S, Blanchette M, Lécuyer E 

Nucleic Acids Res. 2020 , 48(D1):D166-D173. 

(https://pubmed.ncbi.nlm.nih.gov/31724725/)

  2019
 

Bioinformatics Approaches to Gain Insights into cis-Regulatory Motifs Involved in mRNA Localization. 

Benoit Bouvrette LP, Blanchette M, Lécuyer E 

Adv Exp Med Biol. 2019, 1203:165-194. 

(https://pubmed.ncbi.nlm.nih.gov/31811635/)

 

A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster. 

Kong J, Han H, Bergalet J, Bouvrette LPB, Hernández G, Moon NS, Vali H, Lécuyer E, Lasko P

Sci Rep. 2019, 9:13779. doi: 10.1038/s41598-019-50357-z.

(https://pubmed.ncbi.nlm.nih.gov/31551467/)

 

Prediction of mRNA subcellular localization using deep recurrent neural networks. 

Yan Z, Lécuyer E, Blanchette M

Bioinformatics. 2019, 35:i333-i342. 

(https://pubmed.ncbi.nlm.nih.gov/31510698/)

 

Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. 

Fang MY, Markmiller S, Vu AQ, Javaherian A, Dowdle WE, Jolivet P, Bushway PJ, Castello NA, Baral A, Chan MY, Linsley JW, Linsley D, Mercola M, Finkbeiner S, Lécuyer E, Lewcock JW, Yeo GW

Neuron. 2019, 103:802-819.

(https://pubmed.ncbi.nlm.nih.gov/31272829/)

 

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription. 

Xiao R, Chen JY, Liang Z, Luo D, Chen G, Lu ZJ, Chen Y, Zhou B, Li H, Du X, Yang Y, San M, Wei X, Liu W, Lécuyer E, Graveley BR, Yeo GW, Burge CB, Zhang MQ, Zhou Y, Fu XD

Cell. 2019, 178: 107-121.

(https://pubmed.ncbi.nlm.nih.gov/31251911/)